MAIN CAST
Zaijian Jaranilla as Gabriel "Santino Guillermo" M. Policarpio/Rodrigo - A kind-hearted and clever young boy. Longing for the love of his real mother, he finds a friend in the person of "Bro" (Jesus Christ), who helps him change the lives of the people in their town. Known for his healing powers. He is Enrique and Teresa's biological son.
Albert Martinez as Mayor Enrique D. Rodrigo/ Gonzalvo Policarpio† - The mayor of Bagong Pag-asa. His lust for wealth and power will drive him to do illegal acts. He never treats Stella as his real daughter; it is revealed later on that Enrique is, in fact, not her biological father. He is Santino's biological father, but didn't knew about it from the start, and he later gives in, developing a sense of compassion for the boy. Later on in the story, he is actually the child of the couple who was killed when Doña Anita was taking over the land he was living on before. Now, he finally married Tilde. He was killed by his younger brother Robert after saving Santino's life and backing out of the mayoralty race, but not before informing Santino of his parentage to the boy.
Dina Bonnevie as Malena Rodriguez-Rodrigo/Policarpio† - The wife of Enrique. She will do everything to prove her love for her husband. Coming from a wealthy family, Malena envied her sister Selda's intelligence and love with Mario, for she loved him too. This pushed her to commit wrong deeds. Underneath her beauty and glamor is a dark secret that continues to haunt her: she is the only one who knows Santino's biological mother. It was later revealed in a flashback that she accidentally killed Santino's mother. She is initially mistaken to be Santino's mother. She was once the only one who can prove that Santino is indeed Enrique's son with Teresa until it was later revealed that Tilde also knows about Malena's hidden secret. Later, after being involved in a tragic accident along with Rico, Malena is forced to get help from Santino causing her to forget her anger against Santino and accept him as a friend. Irony takes its place after she and Tilde comes face to face in the place where she accidentally killed Teresa. After a fight, Tilde accidentally pushed and killed Malena similarly to the way Malena killed Teresa.
Tonton Gutierrez as Mario Sta. Maria - A loyal policeman whose terminally-ill daughter Joy was miraculously healed by Santino. He is Selda's husband, Malena's ex-lover and Stella's real father. He, however, was dismissed from service for alleged insubordination and absence without leave, but resumed with the help of Santino and the townspeople. He nearly separated from Selda. According to several mentions from his superior, his father was also a loyal policeman who was shamefully dismissed by false charges accused against him, causing him to die as a broken man. Now, he wants to challenge Enrique by running against him in the upcoming mayoral elections.
Maja Salvador as Stella R. Sta. Maria - The obedient daughter of Enrique and Malena. She treats Santino as her younger brother. It is revealed that her biological father is Mario. She was once the girlfriend of Cocoy. She later leaves her parents for their differences, and moves in with Selda and Mario's. Stella went to the States but has now returned together with her grandmother. As she returns to Bagong Pag-asa, her anger to Cocoy still emerged until she found out the truth and came back with him. Later on the series, she was kidnapped by prostitute dealers after trying to visit her mother in a beachhouse. Stella tried to escape or the goons, but accidentally lit a fire and cause an explosion. As the Bagong Pag-asa police have witnessed, they have claimed Stella is deceased, until it was revealed that she did survive the explosion. Stella sadly haven't spent much time with her mother as when she returned to Bagong Pag-asa, the household was currently having Malena's funeral.
Rayver Cruz as Francisco "Cocoy" Bautista - An orphaned young man who works as an assistant at the monastery. He was previously detained several times for petty crimes. He is currently in a relationship with Stella, but they both broke up when Stella asked to, and further distanced away when Stella was sent to the US. But then after explaining everything to her, they came back together. Cocoy have applied for a scholarship in a college to prove that he's worthy for Stella. He plays as part of a varsity team for basketball in college.
Dominic Ochoa as Fr. Jose - Serves as the cook in the monastery. Santino considers him to be a father-figure. It was revealed by Enrique that he had a wife and a child who were killed in a car accident years prior to the setting, and Father Jose was the one blamed for their deaths.Later on the series, after being ashamed on breaking the seal of confession to save Santino, he quit the priesthood. However, this gave him an opportunity to legally adopt Santino. Father Jose formerly worked as a chef (where he later resigned) in a mansion, where, apparently, Enrique and his brother are hiding their gambling place.
Desiree del Valle as Clautilde Katerina "Tilde" Magdayo-Rodrigo/Policarpio - The mayor's mistress, who (formerly) worked as a prostitute, turned (2nd) wife of the Mayor. She helps in executing the mayor's orders in threatening Santino and the priests. It was later revealed that she's pregnant with Enrique's son. Later in the series, it was revealed that Tilde also knows that Malena killed her friend Teresa; she used this to threaten Malena so that the latter would separate with Enrique, which would ultimately result in Tilde finally having Enrique back in her hands. After a fight with Malena, she accidentally killed Malena after pushing her in a hill. Months after Malena's death, Enrique married Tilde, in the midst of an ongoing crisis in Bagong Pag-Asa. She was arrested after authorities have already known the truth about Malena's death, but escaped after pretending to go into labor.
Precious Lara Quigaman as Criselda "Selda" Rodriguez-Sta. Maria - The wife of Mario, the mother of Joy, and the younger sister of Malena. She works as a policewoman. Santino looks up to her as a mother-figure. Along with her sister Malena, she also came from a rich family but she gave up her lifestyle in order to be with her lover, Mario and she nearly separated from Mario after learning that Stella is Mario's daughter. Selda is currently pregnant with her second child.
Lito Pimentel as Fr. Gregorio "Ringo" - A priest who left his life of parties and music to become a priest. His true past was revealed when Enrique was uncovering the dirty secrets of the monastery's priests. Father Ringo was an ex-convict for theft, and his calling to the priesthood came when he served as a sacristan during his time in prison. He is called 'Ringo' because he is the one who rings the church bells.
Jaime Fabregas as Fr. Anthony - The rector and rigid chief administrator of the monastery. Underneath his strict demeanor lies his love and concern for Santino. Mayor Enrique attempted to kill him, but Santino healed him before he die. It's unsure if Fr. Anthony had a vision of Bro while Santino is healing him.
Bro (Jesus Christ) - Santino's Friend and Confidant, and the source of his healing powers. It is to Him that Santino runs to for help or consolation. He appears to Santino from the statue in the cemetery. His face is never revealed whenever He is seen talking with Santino; camera shots of Him consist mostly of those from behind the back, or from the chest downwards or with the face obscured in some other manner.
Satan - the main antagonist of the series and an evil parody of Bro who gave Rico psychic powers in order to foretell misfortunes in Bagong Pag-Asa; he influenced Santino in order for the latter to leave Bagong Pag-asa and the former to execute his evils in that town.
EXTENDED CAST
Ogie Diaz as Renato "Atong" Arguelles - the flamboyantly gay husband of Baby. Sometimes parodies Philippine broadcaster/TV host Gus Abelgas, specifically his voice.
Arlene Muhlach as Viviana "Baby" Arguelles - the "Queen Of Gossips", and Malena's best friend. When Baby discovered that Malena's earrings are the same with Santino's, she suspected Malena as being Santino's mother.
Victor Basa as Fr. John Delgado - the son of a wealthy haciendero, his father had a lot of dreams for him, but he entered the religious life, estranging him from his father. Later, John and his father reconciled, the latter accepting John's choice.
Badjie Mortiz as Fr. Paul Makopa - He is the monastery's gatekeeper. He was also shot by Tatay Ben's men, but was healed by Santino.
David Chua as Fr. Chino "Chi" Wang - The treasurer of the monastery; a Chinese-Filipino and apparently was supposed to become a businessman, but eventually chose the priesthood. His sister has sought comfort from him after running away from an arranged marriage with a man she did not love.
Andre Tiangco as Fr. George - Father "Linis" (Clean), this obsessive-compulsive priest is always seen with a towel draped on one shoulder, and carrying brooms and mops. He leads the priests in keeping the monastery clean.
Ruben Gonzaga as Fr. Patrick - takes care of the monastery's little farm and garden. His family engages in fishing for a living; he discovered on a visit to his family that his younger brother, Jepoy, was involved in dynamite fishing.
Edgar Sandalo as Fr. Jude - one of the 12 priests in the monastery, Father Jude is characterized as a grumpy man with a white moustache, beard and hair.
Timothy Lambert Chan as Rico R. Rodrigo/Policarpio - Enrique and Malena's son and half-brother to Stella. He started befriending Santino after seeing the boy's good nature. Rico is not privy to the secret of Santino being his paternal half-brother. After Enrique died, Rico was discovered to possess the power of foresight (mostly tragic events).
Phebe Khae Arbotante as Joy R. Sta. Maria - Mario and Selda's daughter, and Stella's half-sister/cousin. When she was terminally ill, she was saved by Santino. As one of Santino's closest friends, she became a member of Santino's Angels.
ADDITIONAL CAST
Francis Magundayao as Paco - one of Santino's closest friends. He used to beg with his grandmother by acting very poor but after his grandmother got involved in accident and apparently healed by Santino, He promised to God that he will never do those things again. He also became one of the scholars of the monastery and as Santino's friends became a member of Santino's Angels.
Miguelito de Guzman as Alfred - He became friends with Santino after running away from home after his parents are about to have divorce. He's also a member of Santino's Angels.
Liza Lorena as Doña Anita Rodriguez - Malena & Selda's mother. After living in the United States for several years, she returns to the Philippines to pay a visit to the family together with Stella and Robert, her personal assistant. Doña Anita was imprisoned after being formally charged and being proclaimed guilty after being accused for the murder that happened to Bagong Pag-asa 30 years ago. On the day of Malena's burial, she was acquitted on all charges due to lack of evidence.
Michael Conan as Dante Maoricio - a new Police Officer assigned for his mission to Bagong Pag-asa.
Ron Morales as Robert Sanchez/ Gustavo Policarpio† - Doña Anita's personal assistant who practically takes care of every files Doña Anita got. He has worked for Doña Anita since she was in the United States, he previously took care of Doña Anita's case. It is later revealed that he is the younger brother of Enrique or Gonsalvo Policarpio. Shot Enrique.
Jerry O'Hara as Senior Superintendent Raul Guevarra - the Chief of Police in Bagong Pag-asa. Seems to have known (and possibly have worked with) Mario's father, also witnesing his downfall.
Rosalie, Kimberly, and Jennifer - a trio of idle ladies who do nothing but spread rumours. The additional comic relief of the show, the three always rush into the Arguelles' store to gossip, only to end up being hilariously dismissed by Atong, who accompanies their expulsion with shouts of "Layas!" (Tagalog for "Go away!").
Erin Panlilio as Grace - Moy & Jackie's daughter. Grace didn't want to live with her mom because she knows for the fact that Jackie have abandoned them due to her father's lack of money. As part of her wishes, she only wants to be with her father, her grandfather Pilo and their dog, Rocky. Now, she's going to the same school with Santino and his friends (Rico, Joy, Alfred & Paco).
Thank you, Wikipedia for this information.